The mitochondrial regulator PGC1α is induced by cGMP–PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure-Reference-Cited by-同舟云学术

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The mitochondrial regulator PGC1α is induced by cGMP–PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure

Published:2021-11-19 Issue:1 Volume:596 Page:17-28
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Letters

Author:

Zhu Guangshuo¹,Ueda Kazutaka²³,Hashimoto Masaki²^ORCID,Zhang Manling¹,Sasaki Masayuki¹,Kariya Taro¹,Sasaki Hideyuki¹,Kaludercic Nina¹,Lee Dong‐ik¹,Bedja Djahida¹,Gabrielson Matthew¹,Yuan Yuan¹,Paolocci Nazareno¹,Blanton Robert M.³,Karas Richard H.³,Mendelsohn Michael E.³⁴,O’Rourke Brian¹,Kass David A.¹^ORCID,Takimoto Eiki¹²^ORCID

Affiliation:

1. Division of Cardiology Department of Medicine Johns Hopkins University School of Medicine Baltimore MD USA

2. Department of Cardiovascular Medicine The University of Tokyo Graduate School of Medicine Tokyo Japan

3. Molecular Cardiology Research Institute and Division of Cardiology Tufts Medical Center Boston MA USA

4. Cardurion Pharmaceuticals Boston MA USA

Funder

National Institutes of Health

American Heart Association

Muscular Dystrophy Association

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.14228

Reference38 articles.

1. Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G

2. Cyclic GMP-Dependent Signaling in Cardiac Myocytes

3. Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction

4. PDE5 Inhibition With Sildenafil Improves Left Ventricular Diastolic Function, Cardiac Geometry, and Clinical Status in Patients With Stable Systolic Heart Failure

5. Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

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1. Exploring the Multifaceted Potential of Sildenafil in Medicine;Medicina;2023-12-17

2. Multi-omics approach for identification of molecular alterations of QiShenYiQi dripping pills in heart failure with preserved ejection fraction;Journal of Ethnopharmacology;2023-10

3. Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis;Frontiers in Aging;2023-06-13

4. Chitosan Nanoparticles Alleviated the Adverse Effects of Sildenafil on the Oxidative Stress Markers and Antioxidant Enzyme Activities in Rats;Oxidative Medicine and Cellular Longevity;2023-01-31

5. Beyond Erectile Dysfunction: cGMP-Specific Phosphodiesterase 5 Inhibitors for Other Clinical Disorders;Annual Review of Pharmacology and Toxicology;2023-01-20

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