Internalisation and toxicity of amyloid‐β 1‐42 are influenced by its conformation and assembly state rather than size-Reference-Cited by-同舟云学术

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Internalisation and toxicity of amyloid‐β 1‐42 are influenced by its conformation and assembly state rather than size

Published:2020-09-11 Issue:21 Volume:594 Page:3490-3503
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Lett

Author:

Vadukul Devkee M.¹²,Maina Mahmoud¹³^ORCID,Franklin Hannah¹,Nardecchia Astrid¹,Serpell Louise C.¹,Marshall Karen E.¹^ORCID

Affiliation:

1. Dementia Research group Sussex Neuroscience School of Life Sciences University of Sussex Falmer E Sussex UK

2. CEMO‐Alzheimer Dementia group Institute of Neuroscience Université catholique de Louvain Brussels Belgium

3. College of Medical Sciences Yobe State University Nigeria

Funder

Alzheimer's Research Trust

Medical Research Council

Alzheimer's Society

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.13919

Reference87 articles.

1. The amyloid hypothesis of Alzheimer's disease at 25 years

2. The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

3. Alzheimer's Disease: A Central Role for Amyloid

4. Alzheimer’s amyloid fibrils: structure and assembly

5. The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

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1. Hybrid Amyloid Quantum Dot Nano-Bio Assemblies to Probe Neuroinflammatory Damage;ACS Chemical Neuroscience;2024-08-15

2. Amyloid beta 1‐40 and 1‐42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity;Journal of Neurochemistry;2024-08-12

3. Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling;eLife;2024-07-19

4. Protective effect of trehalose sugar on amyloid-membrane interactions using BLM electrophysiology;Biophysical Journal;2024-06

5. Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling;2024-05-30

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