Structural insight into the interaction ofO-acetylserine sulfhydrylase with competitive, peptidic inhibitors by saturation transfer difference-NMR-Reference-Cited by-同舟云学术

Structural insight into the interaction ofO-acetylserine sulfhydrylase with competitive, peptidic inhibitors by saturation transfer difference-NMR

Published:2016-03-22 Issue:7 Volume:590 Page:943-953
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Lett

Author:

Benoni Roberto¹,Pertinhez Thelma A.²,Spyrakis Francesca³,Davalli Silvia⁴,Pellegrino Sara⁵,Paredi Gianluca⁶,Pezzotti Angelica⁶,Bettati Stefano¹⁷,Campanini Barbara⁶,Mozzarelli Andrea⁶⁷⁸

Affiliation:

1. Department of Neurosciences; University of Parma; Italy

2. Department of Oncology and Advanced Techniques; Arcispedale Santa Maria Nuova-IRCCS; Reggio Emilia Italy

3. Department of Food Sciences; University of Parma; Italy

4. Aptuit, Medicine Research Center; Verona Italy

5. Department of Pharmaceutical Sciences; Section of General and Organic Chemistry ‘A. Marchesini’; University of Milan; Italy

6. Department of Pharmacy; University of Parma; Italy

7. National Institute for Biostructures and Biosystems; Rome Italy

8. Institute of Biophysics; CNR; Pisa Italy

Funder

Multiple Sclerosis Center of Atlanta

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference51 articles.

1. The enzymic synthesis of L-cysteine in Escherichia coli and Salmonella typhimurium;Kredich;J Biol Chem,1966

2. Purification and characterization of O-acetylserine (thiol) lyase from spinach chloroplasts;Droux;Arch Biochem Biophys,1992

3. Purification and characterization of L-serine transacetylase and O-acetyl-L-serine sulfhydrylase from kidney bean seedlings (Phaseolus vulgaris);Smith;Biochim Biophys Acta,1971

4. Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex;Schnell;J Biol Chem,2007

5. Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase;Chinthalapudi;Proteins,2008

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Advancements in inhibitors of crucial enzymes in the cysteine biosynthetic pathway: Serine acetyltransferase and O‐acetylserine sulfhydrylase;Chemical Biology & Drug Design;2024-07

2. Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR;Protein & Peptide Letters;2023-09

3. Insights into the Substrate Uptake Mechanism of Mycobacterium Tuberculosis Ribose 5-Phosphate Isomerase and Perspectives on Drug Development;Biophysica;2023-03-01

4. Tylosin Inhibits Streptococcus suis Biofilm Formation by Interacting With the O-acetylserine (thiol)-lyase B CysM;Frontiers in Veterinary Science;2022-01-28

5. Thiol targets in drug development to combat bacterial infections;Redox Chemistry and Biology of Thiols;2022