Design of sodium channel ligands with defined selectivity - a case study in scorpion alpha-toxins
Author:
Affiliation:
1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry; Russian Academy of Sciences; Moscow Russia
2. Moscow Institute of Physics and Technology (State University); Russia
3. Toxicology and Pharmacology; University of Leuven; Belgium
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Reference35 articles.
1. Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution;Rodriguez de la Vega;Toxicon,2005
2. Target-driven evolution of scorpion toxins;Zhang;Sci Rep,2015
3. Scorpion toxins affecting sodium current inactivation bind to distinct homologous receptor sites on rat brain and insect sodium channels;Gordon;J Biol Chem,1996
4. Voltage-gated sodium channel modulation by scorpion alpha-toxins;Bosmans;Toxicon,2007
5. International union of pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels;Catterall;Pharmacol Rev,2005
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Scorpion Neurotoxin BeM9 Derivative Uncovers Unique Interaction Mode with Nav1.5 Sodium Channel Isoform;Russian Journal of Bioorganic Chemistry;2024-08
2. A scorpion toxin affecting sodium channels shows double cis–trans isomerism;FEBS Letters;2023-08-07
3. A Buthus martensii Karsch scorpion sting targets Nav1.7 in mice and mimics a phenotype of human chronic pain;Pain;2021-07-08
4. Derivative of Scorpion Neurotoxin BeM9 Is Selective for Insect Voltage-Gated Sodium Channels;Russian Journal of Bioorganic Chemistry;2021-07
5. Scorpion toxin MeuNaTxα‐1 sensitizes primary nociceptors by selective modulation of voltage‐gated sodium channels;The FEBS Journal;2020-11-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3