Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice

Author:

Pang Zhengda12,Higuchi Masayoshi1,Koriyama Hiroshi3,Yoshida Shota4,Kurinami Hitomi3,Shimamura Munehisa3,Takami Yoichi1,Rakugi Hiromi1,Morishita Ryuichi4,Nakagami Hironori3

Affiliation:

1. Department of Geriatric and General Medicine; Osaka University Graduate School of Medicine; Japan

2. Department of Physiology and Pathophysiology; School of Medicine; Xi'an Jiaotong University; China

3. Department of Health Development and Medicine; Osaka University Graduate School of Medicine; Japan

4. Department of Clinical Gene Therapy; Osaka University Graduate School of Medicine; Japan

Funder

Japan IDDM network

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference32 articles.

1. Type 1 diabetes;Daneman;Lancet,2006

2. beta-Cell death during progression to diabetes;Mathis;Nature,2001

3. Type 1 diabetes: new perspectives on disease pathogenesis and treatment;Atkinson;Lancet,2001

4. The global burden of youth diabetes: perspectives and potential;Aanstoot;Pediatr Diabetes,2007

5. Therapy with GAD in diabetes;Ludvigsson;Diabetes Metab Res Rev,2009

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