A small molecule chaperone rescues the stability and activity of a cancer‐associated variant of NAD(P)H:quinone oxidoreductase 1in vitro-Reference-Cited by-同舟云学术

A small molecule chaperone rescues the stability and activity of a cancer‐associated variant of NAD(P)H:quinone oxidoreductase 1in vitro

Published:2019-10-30 Issue:3 Volume:594 Page:424-438
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Lett

Author:

Strandback Emilia¹,Lienhart Wolf‐Dieter¹,Hromic‐Jahjefendic Altijana²³,Bourgeois Benjamin⁴,Högler Anja¹,Waltenstorfer Daniel¹,Winkler Andreas¹,Zangger Klaus⁵,Madl Tobias⁴⁶^ORCID,Gruber Karl²,Macheroux Peter¹^ORCID

Affiliation:

1. Institute of Biochemistry Graz University of Technology Austria

2. Institute of Molecular Biosciences University of Graz Austria

3. Department of Genetics and Bioengineering Faculty of Engineering and Natural Sciences International University of Sarajevo Sarajevo Bosnia and Herzegovina

4. Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry Medical University of Graz Austria

5. Institute of Chemistry University of Graz Austria

6. BioTechMed‐Graz Austria

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.13636

Reference39 articles.

1. NAD(P)H:Quinone Oxidoreductase 1: Role as a Superoxide Scavenger

2. NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33ING1b

3. A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

4. A Model for NAD(P)H: Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy

5. NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones

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