Cardiac-specific down-regulation of carnitine palmitoyltransferase-1b (CPT-1b) prevents cardiac remodeling in obese mice

Author:

Zhang Yijie123,Fang Xianlong4,Dai Mingyan123,Cao Quan123,Tan Tuantuan5,He Wenbo123,Huang Yan123,Chu Liang4,Bao Mingwei123

Affiliation:

1. Department of Cardiology; Renmin Hospital of Wuhan University; Wuhan People's Republic of China

2. Cardiovascular Research Institute, Wuhan University; Wuhan People's Republic of China

3. Hubei Key Laboratory of Cardiology; Wuhan People's Republic of China

4. State Key Laboratory of Cell Biology; Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Shanghai People's Republic of China

5. Department of Ultrasonography; Renmin Hospital of Wuhan University; Wuhan People's Republic of China

Funder

Natural Science Foundation of China

Natural Science Foundation of Shanghai

Publisher

Wiley

Subject

Nutrition and Dietetics,Endocrinology,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Reference40 articles.

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2. Global trend in overweight and obesity and its association with cardiovascular disease incidence;Yatsuya;Circ J,2014

3. Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria;Niemann;J Am Coll Cardiol,2011

4. Cardiomyocyte apoptosis in animal models of obesity;Trivedi;Curr Hypertens Rep,2008

5. Myocardial myocyte remodeling and fibrosis in the cardiometabolic syndrome;Hayden;J Cardiometab Syndr,2006

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