Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes

Author:

Rotroff DM12,Shahin MH3,Gurley SB4,Zhu H5,Motsinger‐Reif A12,Meisner M2,Beitelshees AL6,Fiehn O78,Johnson JA3,Elbadawi‐Sidhu M7,Frye RF3,Gong Y3,Weng L3,Cooper‐DeHoff RM3,Kaddurah‐Daouk R59

Affiliation:

1. Department of StatisticsNorth Carolina State UniversityRaleigh North Carolina USA

2. Bioinformatics Research CenterNorth Carolina State UniversityRaleigh North Carolina USA

3. Department of Pharmacotherapy and Translational Research and Center for PharmacogenomicsUniversity of FloridaGainesville Florida USA

4. Department of MedicineDuke University Medical Center and Durham Veterans Affairs Medical CenterDurham North Carolina USA

5. Department of Psychiatry and Behavioral SciencesDuke UniversityDurham North Carolina USA

6. Department of MedicineUniversity of Maryland School of MedicineBaltimore Maryland USA

7. UC Davis Genome CenterUniversity of California DavisDavis California USA

8. King Abdulaziz UniversityJeddah Saudi‐Arabia

9. Duke Institute for Brain SciencesDuke UniversityDurham North California USA

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

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