Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation
Author:
Affiliation:
1. AstraZeneca PharmaceuticalsWaltham Massachusetts USA
2. Ann Arbor Pharmacometrics GroupAnn Arbor Michigan USA
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12099
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3. Novel opioid antagonists for opioid-induced bowel dysfunction
4. A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation
5. Incidence, Prevalence, and Management of Opioid Bowel Dysfunction
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