Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6-Reference-Cited by-同舟云学术

Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6

Published:2016-07 Issue:7 Volume:5 Page:367-376
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Ke A¹,Barter Z¹,Rowland-Yeo K¹,Almond L¹

Affiliation:

1. Simcyp Limited (a Certara Company); Sheffield UK

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/psp4.12088/fullpdf

Reference48 articles.

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2. Merck & Co. I. Crixivan (Indinavir Sulfate): prescribing information 2002 http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20685s050s053s056lbl.pdf

3. GlaxoSmithKline. Lexiva (Fosamprenavir Calcium): prescribing information 2003 http://www.accessdata.fda.gov/drugsatfda_docs/label/2003/21548_levixa_lbl.pdf

4. GlaxoSmithKline. Tivicay (Dolutegravir): highlights of prescribing information 2013 http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204790lbl.pdf

5. Janssen. Olysio (Simeprevir): Highlights of prescribing information 2013 http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/205123s000lbledt.pdf

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