Human Cardiac Ventricular‐Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two‐Tiered Assay for Inotropic Responses-Reference-Cited by-同舟云学术

Human Cardiac Ventricular‐Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two‐Tiered Assay for Inotropic Responses

Published:2019-03-28 Issue:2 Volume:106 Page:402-414
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Keung Wendy¹²,Chan Patrick K.W.¹,Backeris Peter C.³,Lee Eugene K.⁴,Wong Nicodemus¹,Wong Andy O.T.⁴,Wong Gabriel K.Y.⁴,Chan Camie W.Y.⁴,Fermini Bernard⁵,Costa Kevin D.³⁴,Li Ronald A.¹²⁴

Affiliation:

1. Ming Wai Lau Centre for Reparative MedicineKarolinska Institutet Shatin Hong Kong

2. Dr. Li Dak‐Sum Research CentreThe University of Hong Kong Pokfulam Hong Kong

3. Cardiovascular Research CenterIcahn School of Medicine at Mount Sinai New York New York, USA

4. Novoheart Vancouver British Columbia Canada

5. Global Safety PharmacologyPfizer Worldwide Research and Development Groton Connecticut USA

Funder

Innovation and Technology Commission

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1385

Reference50 articles.

1. Estimating The Cost Of New Drug Development: Is It Really $802 Million?

2. Cardiac electrophysiology in mice: a matter of size

3. The dog's role in the preclinical assessment of QT interval prolongation;Gralinski M.R.;Toxicol. Pathol.,2003

4. The Utility of the Small Rodent Electrocardiogram in Toxicology

5. Animal models of toxicology testing: the role of pigs

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