Postmastectomy radiotherapy in breast reconstruction: Current controversies and trends

Author:

Zhang Honghong1ORCID,Song Dandan1ORCID,Xie Liangxi1,Zhan Ning1,Xie Wenjia1,Zhang Jianming2

Affiliation:

1. Department of Radiation Oncology, Xiang'an Hospital of Xiamen University, Cancer Research Center, School of Medicine Xiamen University, Xiang'an Xiamen Fujian China

2. Fujian Provincial Key Laboratory of Intelligent Identification and Control of Complex Dynamic System, Quanzhou Institute of Equipment Manufacturing, Haixi Institutes Chinese Academy of Sciences Quanzhou Fujian China

Abstract

AbstractBreast cancer is the most common cancer among women worldwide. Postmastectomy radiotherapy (PMRT) is an essential component of combined therapy for early‐stage, high‐risk breast cancer. Breast reconstruction (BR) is often considered for patients with breast cancer who have undergone mastectomy. There has been a considerable amount of discussion about the optimal approach to combining PMRT with BR in the treatment of breast cancer. PMRT may increase the risk of complications and prevent good aesthetic results after BR, while BR may increase the complexity of PMRT and the radiation dose to surrounding normal tissues. The purpose of this review is to give a broad overview and summary of the current controversies and trends in PMRT and BR in the context of the most recent literature available.

Publisher

Wiley

Subject

Pharmacology (medical),Cancer Research,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Drug Discovery,Oncology

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