Positive predictive values for detection of trisomies 21, 18 and 13 and termination of pregnancy rates after referral for advanced maternal age, first trimester combined test or ultrasound abnormalities in a national screening programme (2007-2009)

Author:

Siljee Jacqueline E.1,Knegt Alida C.2,Knapen Maarten F. C. M.3,Bekker Mireille N.4,Visser Gerard. H. A.5,Schielen Peter C. J. I.1

Affiliation:

1. Reference Laboratory for Pre- and Neonatal Screening/Laboratory for Infectious Diseases and Screening; National Institute for Public Health and the Environment; Bilthoven The Netherlands

2. Department of Clinical Genetics; University Medical Center Amsterdam; Amsterdam The Netherlands

3. Department of Obstetrics and Prenatal Medicine; Erasmus MC Rotterdam, Stichting Prenatale Screening; Rotterdam The Netherlands

4. Department of Obstetrics, Prenatal Diagnosis and Therapy; Radboud University Medical Center; Nijmegen The Netherlands

5. Department of Obstetrics; University Medical Center Utrecht; The Netherlands

Publisher

Wiley

Subject

Genetics (clinical),Obstetrics and Gynecology

Reference9 articles.

1. Trends in the utilization of invasive prenatal diagnosis in The Netherlands during 2000-2009;Lichtenbelt;Prenat Diagn,2011

2. Factors determining uptake of invasive testing following first-trimester combined testing;Lichtenbelt;Prenat Diagn,2013

3. Schielen PCJI Quality control parameters of Dutch Down's syndrome screening laboratories 2009 2011 http://www.rivm.nl/dsresource?objectid=rivmp:119025&type=org&disposition=inline&ns_nc=1

4. Fracheboud J Van Agt HME De Koning , HJ Monitoring 2010 http://www.rivm.nl/dsresource?objectid=rivmp:193263&type=org&disposition=inline

5. Performance of first-trimester serum screening for trisomy 21 before and from 11 + 0 weeks of gestational age in The Netherlands;Kuc;Prenat Diagn,2010

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