Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis-Reference-Cited by-同舟云学术

Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis

Published:2020-03-15 Issue:5 Volume:4 Page:724-738
ISSN:2471-254X
Container-title:Hepatology Communications
language:en
Short-container-title:Hepatol Commun

Author:

Ueno Kazuko¹²,Aiba Yoshihiro³,Hitomi Yuki²⁴,Shimoda Shinji⁵,Nakamura Hitomi³,Gervais Olivier⁶,Kawai Yosuke¹²,Kawashima Minae⁷,Nishida Nao¹²,Kohn Seik‐Soon¹²,Kojima Kaname⁸,Katsushima Shinji⁹,Naganuma Atsushi⁹,Sugi Kazuhiro⁹,Komatsu Tatsuji⁹,Mannami Tomohiko⁹,Matsushita Kouki⁹,Yoshizawa Kaname⁹,Makita Fujio⁹,Nikami Toshiki⁹,Nishimura Hideo⁹,Kouno Hiroshi⁹,Kouno Hirotaka⁹,Ohta Hajime⁹,Komura Takuya⁹,Tsuruta Satoru⁹,Yamauchi Kazuhiko⁹,Kobata Tatsuro⁹,Kitasato Amane¹⁰,Kuroki Tamotsu³¹⁰¹¹,Abiru Seigo³,Nagaoka Shinya³,Komori Atsumasa³¹¹,Yatsuhashi Hiroshi³¹¹,Migita Kiyoshi³¹²,Ohira Hiromasa¹²,Tanaka Atsushi¹³,Takikawa Hajime¹³,Nagasaki Masao⁶,Tokunaga Katsushi¹²,Nakamura Minoru³⁹¹¹¹⁴,

Affiliation:

1. Genome Medical Science Project National Center for Global Health and Medicine Tokyo Japan

2. Department of Human Genetics Graduate School of Medicine University of Tokyo Tokyo Japan

3. Clinical Research Center National Hospital Organization of Nagasaki Medical Center Omura Japan

4. Department of Microbiology Hoshi University School of Pharmacy and Pharmaceutical Sciences Tokyo Japan

5. Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences Fukuoka Japan

6. Human Biosciences Unit for the Top Global Course Center for the Promotion of Interdisciplinary Education and Research Kyoto University Kyoto Japan

7. Japan Science and Technology Agency Tokyo Japan

8. Tohoku Medical Megabank Organization Tohoku University Sendai Japan

9. Headquarters of PBC Research National Hospital Organization Study Group for Liver Disease in Japan Omura Japan

10. Department of Surgery National Hospital Organization of Nagasaki Medical Center Omura Japan

11. Department of Hepatology Graduate School of Biomedical Sciences Nagasaki University Omura Japan

12. Department of Gastroenterology and Rheumatic Diseases Fukushima Medical University of Medicine Fukushima Japan

13. Department of Medicine Teikyo University School of Medicine Tokyo Japan

14. Headquarters of PBC‐GWAS Consortium in Japan National Hospital Organization of Nagasaki Medical Center Graduate School of Biomedical Sciences Nagasaki University Omura Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep4.1497

Reference50 articles.

1. Primary Biliary Cirrhosis

2. Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases

3. A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis