The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis

Author:

Kim Nam-Hoon1,Choi Susanna1,Han Eun-Jin1,Hong Bong-Ki1,Choi Soo Youn2,Kwon H. Moo2,Hwang Sue-Yun3,Cho Chul-Soo14,Kim Wan-Uk14

Affiliation:

1. POSTECH-CATHOLIC BioMedical Engineering Institute; The Catholic University of Korea; Seoul Korea

2. School of Nano-Bioscience and Chemical Engineering; Ulsan National Institute of Science and Technology; Ulsan Korea

3. Department of Animal Biotechnology; Graduate School of Biology and Information Technology, Hankyoung National University; Ansung Kyunggi-Do Korea

4. Division of Rheumatology, Department of Internal Medicine; Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea; Seoul Korea

Funder

Korea Health Industry Development Institute

National Research Foundation of Korea

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference44 articles.

1. Bridging the NFAT and NF-κB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress;López-Rodríguez;Immunity,2001

2. The Drosophila NFAT homolog is involved in salt stress tolerance;Keyser;Insect Biochem. Mol. Biol.,2007

3. NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun;Lopez-Rodríguez;Proc. Natl. Acad. Sci. USA,1999

4. The role of NFAT transcription factors in integrin-mediated carcinoma invasion;Jauliac;Nat. Cell Biol.,2002

5. A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis. J. Cell;O'Connor;Sci.,2007

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