A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS)-Reference-Cited by-同舟云学术

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A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS)

Published:2014-06-10 Issue:7 Volume:44 Page:2096-2110
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Negm Ola H.¹²,Mannsperger Heiko A.³,McDermott Elizabeth M.⁴,Drewe Elizabeth⁴,Powell Richard J.¹,Todd Ian¹,Fairclough Lucy C.¹,Tighe Patrick J.¹

Affiliation:

1. School of Life Sciences; The University of Nottingham; UK

2. Medical Microbiology and Immunology Department; Faculty of Medicine, Mansoura University; Mansoura Egypt

3. Department of Molecular Genome Analysis; German Cancer Research Centre; Heidelberg Germany

4. Nottingham University Hospitals National Health Service Trust; Queen's Medical Centre Campus; Nottingham UK

Funder

Jones 1986 Charitable Trust

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201344328/fullpdf

Reference40 articles.

1. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes;McDermott;Cell,1999

2. INFEVERS: the Registry for FMF and hereditary inflammatory disorders mutations;Sarrauste de Menthiere;Nucleic Acids Res.,2003

3. Shedding of mutant tumor necrosis factor receptor superfamily 1A associated with tumor necrosis factor receptor-associated periodic syndrome: differences between cell types;Huggins;Arthritis Rheum.,2004

4. Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour;Todd;Immunology,2004

5. Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function;Rebelo;Arthritis Rheum.,2006

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