Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells

Author:

Boding Lasse1,Hansen Ann K.1,Meroni Germana2,Johansen Bo B.3,Braunstein Thomas H.4,Bonefeld Charlotte M.1,Kongsbak Martin1,Jensen Benjamin A. H.1,Woetmann Anders1,Thomsen Allan R.1,Ødum Niels1,von Essen Marina R.1,Geisler Carsten1

Affiliation:

1. Department of International Health, Immunology and Microbiology; University of Copenhagen; Copenhagen Denmark

2. Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”; Trieste Italy

3. Core Facility for Integrated Microscopy; University of Copenhagen; Copenhagen Denmark

4. Department of Biomedical Sciences; Danish National Research Foundation Centre for Cardiac Arrhythmia; University of Copenhagen; Copenhagen Denmark

Funder

The A.P. M�ller Foundation for the Advancement of Medical Sciences

The Danish Medical Research Council

The Lundbeck Foundation

The Novo Nordisk Founda�tion

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference47 articles.

1. Three-dimensional segregation of supramolecular activation clusters in T cells;Monks;Nature,1998

2. The immunological synapse: a molecular machine controlling T cell activation;Grakoui;Science,1999

3. The immunological synapse of CTL contains a secretory domain and membrane bridges;Stinchcombe;Immunity,2001

4. Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells;Geiger;J. Cell Biol.,1982

5. Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells;Kupfer;J. Immunol.,1984

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