Pairing of T-cell receptor chains via emulsion PCR

Author:

Turchaninova Maria A.1,Britanova Olga V.1,Bolotin Dmitriy A.1,Shugay Mikhail1,Putintseva Ekaterina V.1,Staroverov Dmitriy B.1,Sharonov George1,Shcherbo Dmitriy12,Zvyagin Ivan V.13,Mamedov Ilgar Z.13,Linnemann Carsten4,Schumacher Ton N.4,Chudakov Dmitriy M.13

Affiliation:

1. Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science; Moscow Russia

2. Evrogen JSC; Moscow Russia

3. CEITEC MU; Masaryk University; Brno Czech Republic

4. Division of Immunology; The Netherlands Cancer Institute; Amsterdam The Netherlands

Funder

Molecular and Cell Biology program RAS, Russian Foundation for Basic Research

Ministry of education and science of the Russian Federation

Russian Federation President Grant for young scientists

European Regional Development Fund

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference23 articles.

1. Therapeutic antibodies: past, present and future;Leavy;Nat. Rev. Immunol.,2010

2. T-cell-receptor gene therapy;Schumacher;Nat. Rev. Immunol.,2002

3. Bias in the alphabeta T-cell repertoire: implications for disease pathogenesis and vaccination;Miles;Immunol. Cell Biol.,2011

4. Human x mouse somatic cell hybrid clone secreting immunoglobulins of both parental types;Schwaber;Nature,1973

5. Single, antigen-specific B cells used to generate Fab fragments using CD40-mediated amplification or direct PCR cloning;Lagerkvist;Biotechniques,1995

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