PD-1 regulates extrathymic regulatory T-cell differentiation

Author:

Chen Xiufen1,Fosco Dominick1,Kline Douglas E.12,Meng Liping1,Nishi Saki2,Savage Peter A.2,Kline Justin12

Affiliation:

1. Department of Medicine; University of Chicago Comprehensive Cancer Center; Chicago IL USA

2. Committee on Immunology; University of Chicago Comprehensive Cancer Center; Chicago IL USA

Funder

National Cancer Institute

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference56 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

2. Regulatory T cells and immune tolerance;Sakaguchi;Cell,2008

3. The development and function of regulatory T cells;Workman;Cell. Mol. Life Sci.,2009

4. Control of regulatory T cell development by the transcription factor Foxp3;Hori;Science,2003

5. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3;Bennett;Nat. Genet.,2001

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