Comparison of microbial and transient expression (tobacco plants and plant‐cell packs) for the production and purification of the anticancer mistletoe lectin viscumin-Reference-Cited by-同舟云学术

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Comparison of microbial and transient expression (tobacco plants and plant‐cell packs) for the production and purification of the anticancer mistletoe lectin viscumin

Published:2019-06-29 Issue:9 Volume:116 Page:2236-2249
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Gengenbach Benjamin B.¹²,Keil Linda L.²,Opdensteinen Patrick¹²,Müschen Catherine R.¹²,Melmer Georg³,Lentzen Hans⁴,Bührmann Jens³,Buyel Johannes F.¹²^ORCID

Affiliation:

1. Integrated Production PlatformsFraunhofer Institute for Molecular Biology and Applied Ecology IMEAachen Germany

2. Institute for Molecular BiotechnologyRWTH Aachen UniversityAachen Germany

3. Pharmedartis GmbHAachen Germany

4. MELEMA Pharma GmbHHamburg Germany

Funder

Deutsche Forschungsgemeinschaft

Fraunhofer-Gesellschaft

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27076

Reference86 articles.

1. Mistletoe lectin dissociates into catalytic and binding subunits before translocation across the membrane to the cytoplasm

2. Polyclonal antibodies for specific detection of tobacco host cell proteins can be efficiently generated following RuBisCO depletion and the removal of endotoxins

3. Ricin Poisoning

4. Hosts of Viscum album

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