Dramatic bone remodeling following larotrectinib administration for bone metastasis in a patient with TRK fusion congenital mesoblastic nephroma

Author:

Halalsheh Hadeel1ORCID,McCarville Mary Beth2,Neel Michael3,Reynolds Mark4,Cox Michael C.4,Pappo Alberto S.1

Affiliation:

1. Department of Oncology; St. Jude Children's Research Hospital; Memphis Tennessee

2. Department of Diagnostic imaging; St. Jude Children's Research Hospital; Memphis Tennessee

3. Department of Surgery; St. Jude Children's Research Hospital; Memphis Tennessee

4. Loxo Oncology Inc.; South San Francisco California

Funder

Loxo Oncology, Inc.

Bayer AG

American Lebanese Syrian Associated Charities

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference15 articles.

1. Congenital mesoblastic nephroma of infancy. A report of eight cases and the relationship to Wilms' tumor;Bolande;Pediatrics,1967

2. ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma;Knezevich;Cancer Res,1998

3. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma;Knezevich;Nat Genet,1998

4. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion-cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma;Rubin;Am J Pathol,1998

5. ETV6-NTRK3 in congenital mesoblastic nephroma: a report of the SIOP/GPOH nephroblastoma study;Vokuhl;Pediatr Blood Cancer,2018

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