Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts-Reference-Cited by-同舟云学术

Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts

Published:2019-12 Issue:6 Volume:7 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Gorshkov Kirill¹^ORCID,Wang Amy Q.¹,Sun Wei¹,Fisher Ethan¹,Frigeni Marta²,Singleton Marc¹,Thorne Natasha¹,Class Bradley¹,Huang Wenwei¹^ORCID,Longo Nicola²³^ORCID,Do Minh‐Ha T.⁴,Ottinger Elizabeth A.¹,Xu Xin¹^ORCID,Zheng Wei¹^ORCID

Affiliation:

1. National Center for Advancing Translational Sciences National Institutes of Health Bethesda MD USA

2. Division of Medical Genetics Department of Pediatrics University of Utah Salt Lake City UT USA

3. Associated Regional and University Pathologists (ARUP) Laboratories Salt Lake City UT USA

4. Lumos Pharma Austin TX USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.525

Reference18 articles.

1. X-linked creatine transporter deficiency: clinical aspects and pathophysiology

2. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis

3. Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency

4. Quantification of cyclocreatine in mouse and rat plasma using hydrophilic-interaction ultra-performance liquid chromatography-tandem mass spectrometry

5. High-performance liquid chromatographic assays for free and phosphorylated derivatives of the creatine analogues β-guanidopropionic acid and 1-carboxymethyl-2-iminoimidazolidine (cyclocreatine)

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