Safety, Tolerability, and Pharmacodynamics of Intrathecal Injection of Recombinant Human HGF (KP‐100) in Subjects With Amyotrophic Lateral Sclerosis: A Phase I Trial-Reference-Cited by-同舟云学术

Safety, Tolerability, and Pharmacodynamics of Intrathecal Injection of Recombinant Human HGF (KP‐100) in Subjects With Amyotrophic Lateral Sclerosis: A Phase I Trial

Published:2018-12-11 Issue:5 Volume:59 Page:677-687
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Warita Hitoshi¹,Kato Masaaki¹,Asada Ryuta²,Yamashita Atsuko³,Hayata Daichika³,Adachi Kiichi³,Aoki Masashi¹

Affiliation:

1. Department of Neurology Tohoku University Graduate School of Medicine Sendai Japan

2. Innovative and Clinical Research Promotion Center Gifu University Hospital Gifu Japan

3. Kringle Pharma, Inc. Ibaraki Osaka Japan

Funder

Japan Science and Technology Agency

Ministry of Health, Labour and Welfare

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1355

Reference34 articles.

1. Amyotrophic lateral sclerosis

2. Observational study of patients in Spain with amyotrophic lateral sclerosis: correlations between clinical status, quality of life, and dignity

3. Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis

4. Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis

5. Genotype-phenotype relationships in familial amyotrophic lateral sclerosis with FUS/TLS mutations in Japan

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hepatocyte Growth Factor Delivery to Injured Cervical Spinal Cord Using an Engineered Biomaterial Protects Respiratory Neural Circuitry and Preserves Functional Diaphragm Innervation;Journal of Neurotrauma;2024-08-12

2. Clinical application and potential pluripotent effects of hepatocyte growth factor in spinal cord injury regeneration;Expert Opinion on Investigational Drugs;2024-05-29

3. The Expression of Recombinant Human Hepatocyte Growth Factor in Pichia pastoris;Applied Biochemistry and Microbiology;2024-03-27

4. ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS;Frontiers in Neuroscience;2024-02-08

5. Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis;Frontiers in Molecular Neuroscience;2023-08-24