Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis-Reference-Cited by-同舟云学术

Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis

Published:2013-07-25 Issue:10 Volume:53 Page:1095-1098
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:J Clin Pharmacol

Author:

Dambrova Maija,Skapare-Makarova Elina¹,Konrade Ilze²,Pugovics Osvalds¹,Grinberga Solveiga¹,Tirzite Dace¹,Petrovska Ramona³,Kalvins Ivars¹,Liepins Edgars¹

Affiliation:

1. Latvian Institute of Organic Synthesis; Riga; Latvia

2. Riga Stradins University; Riga; Latvia

3. Latvian Biomedical Research and Study Centre; Riga; Latvia

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.135/fullpdf

Reference19 articles.

1. Mildronate: cardioprotective action through carnitine-lowering effect;Dambrova;Trends Cardiovasc Med.,2002

2. The cardioprotective effect of mildronate is diminished after co-treatment with l-carnitine;Kuka;J Cardiovasc Pharmacol Ther.,2012

3. Mildronate treatment alters gamma-butyrobetaine and l-carnitine concentrations in healthy volunteers;Liepinsh;J Pharm Pharmacol.,2011

4. 3-(2,2,2-Trimethylhydrazinium)propionate (THP)-a novel gamma-butyrobetaine hydroxylase inhibitor with cardioprotective properties;Simkhovich;Biochem Pharmacol.,1988

5. Pharmacokinetic analysis of the cardioprotective effect of 3-(2,2, 2-trimethylhydrazinium) propionate in mice: inhibition of carnitine transport in kidney;Kuwajima;J Pharmacol Exp Ther.,1999

Cited by 52 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Protection of Testis against Lipopolysaccharide-Induced Toxicity: Mildronate-Induced L-Carnitine Depletion as a Modulator of Gut Microbiome Composition and Gastrointestinal Inflammation;Gastrointestinal Disorders;2023-12-05

2. Gut dysbiosis-related thrombosis in inflammatory bowel disease: Potential disease mechanisms and emerging therapeutic strategies;Thrombosis Research;2023-12

3. The role of trimethylamine-N-oxide in the development of cerebrovascular disease (brief review);Neurology, Neuropsychiatry, Psychosomatics;2023-08-15

4. The Association of Circulating L-Carnitine, γ-Butyrobetaine and Trimethylamine N-Oxide Levels with Gastric Cancer;Diagnostics;2023-04-04

5. Gut-Derived Metabolite, Trimethylamine-N-oxide (TMAO) in Cardio-Metabolic Diseases: Detection, Mechanism, and Potential Therapeutics;Pharmaceuticals;2023-03-28