Afadin regulates RhoA/Rho-associated protein kinase signaling to control formation of actin stress fibers in kidney podocytes

Author:

Saito Koji1,Shiino Tatsuhiro1,Kurihara Hidetake2,Harita Yutaka3,Hattori Seisuke4,Ohta Yasutaka1

Affiliation:

1. Division of Cell Biology; Department of Biosciences; School of Science; Kitasato University; Kanagawa Japan

2. Department of Anatomy; School of Medicine; Juntendo University; Tokyo Japan

3. Department of Pediatrics; Graduate School of Medicine; University of Tokyo; Tokyo Japan

4. Division of Biochemistry; School of Pharmaceutical Sciences; Kitasato University; Tokyo Japan

Funder

Japan Society for the Promotion of Science

Kitasato University

Publisher

Wiley

Subject

Cell Biology,Structural Biology

Reference39 articles.

1. ADIP, a novel afadin- and α-actinin-binding protein localized at cell-cell adherens junctions;Asada;J Biol Chem,2003

2. Afadin- and α-actinin-binding protein ADIP directly binds β'-COP, a subunit of the coatmer complex;Asada;Biochem Biophys Res Commun,2004

3. Synaptopondin orchestrates actin organization and cell motility via regulation of RhoA signalling;Asanuma;Nat Cell Biol,2006

4. Rap-afadin axis in control of Rho signaling and endothelial barrier recovery;Birukova;Mol Biol Cell,2013

5. The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the drosophilla embryo;Boettner;Genetics,2003

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