Acute myeloid leukemia with del(9q) is characterized by frequent mutations ofNPM1,DNMT3A, WT1and low expression ofTLE4-Reference-Cited by-同舟云学术

Acute myeloid leukemia with del(9q) is characterized by frequent mutations ofNPM1,DNMT3A, WT1and low expression ofTLE4

Published:2016-10-25 Issue:1 Volume:56 Page:75-86
ISSN:1045-2257
Container-title:Genes, Chromosomes and Cancer
language:en
Short-container-title:Genes Chromosomes Cancer

Author:

Herold Tobias¹²³⁴^ORCID,Metzeler Klaus H.¹²³⁴,Vosberg Sebastian¹²³⁴,Hartmann Luise¹²³⁴,Jurinovic Vindi⁵,Opatz Sabrina¹²³⁴,Konstandin Nikola P.¹,Schneider Stephanie¹,Zellmeier Evelyn¹,Ksienzyk Bianka¹,Graf Alexander⁶,Krebs Stefan⁶,Blum Helmut⁶,Cristina Sauerland Maria⁷,Büchner Thomas⁸,Berdel Wolfgang E.⁸,Wörmann Bernhard J.⁹,Mansmann Ulrich³⁴⁵,Hiddemann Wolfgang¹²³⁴,Bohlander Stefan K.¹⁰,Spiekermann Karsten¹²³⁴,Greif Philipp A.¹²³⁴

Affiliation:

1. Department of Internal Medicine 3; University Hospital Grosshadern, Ludwig-Maximilians-Universität (LMU) München; München Germany

2. Clinical Cooperative Group Leukemia, Helmholtz Center Munich for Environmental Health; München Germany

3. German Cancer Consortium (DKTK); Heidelberg Germany

4. German Cancer Research Center (DKFZ); Heidelberg Germany

5. Institute for Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität (LMU) München; München Germany

6. Laboratory for Functional Genome Analysis (LAFUGA); Gene Center, Ludwig-Maximilians-Universität (LMU) München; München Germany

7. Institute of Biostatistics and Clinical Research, University of Münster; Münster Germany

8. Department of Medicine A-Hematology, Oncology and Pneumology; University of Münster; Münster Germany

9. Department of Hematology, Oncology and Tumor Immunology; Charité University Medicine; Campus Virchow Berlin Germany

10. Department of Molecular Medicine and Pathology; The University of Auckland; Auckland New Zealand

Funder

The German Cancer Aid

the Wilhelm-Sander-Stiftung

the Ludwig-Maximilians-Universität

Leukaemia & Blood Cancer New Zealand and the family of Marijanna Kumerich

Publisher

Wiley

Subject

Cancer Research,Genetics

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5. Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival;Dayyani;Blood,2008

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