Developing a robust LC-MS/MS method to quantify Zn-DTPA, a zinc chelate in human plasma and urine

Author:

Yu Lin12,Meng Fanhua1,Guo Miao2,Yang Ying2,He Jianchang3,Dong Junxing1,Guo Jifen4ORCID,Peng Shuangqing2

Affiliation:

1. Academy of Military Medicine, Academy of Military Sciences; Beijing People's Republic of China

2. Institute of Disease Control and Prevention, People's Liberation Army; Beijing People's Republic of China

3. Kunming General Hospital of Chengdu Military Region; Kunming People's Republic of China

4. Wanshu (Beijing) Pharmaceutical Technology Co. Ltd; Beijing People's Republic of China

Funder

National Major Scientific and Technological Special Project

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference19 articles.

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2. Medical countermeasures against nuclear threats: Radionuclide decorporation agents;Cassatt;Radiat Research,2008

3. Simultaneous quantification of acetaminophen and five acetaminophen metabolites in human plasma and urine by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry: Method validation and application to a neonatal pharmacokinetic study;Cook;Journal of Chromatography B: Analytical Technology in Biomedicine and Life Sciences,2015

4. Rapid spectrophotometric determination of diethylenetriaminepentaacetic acid (DTPA) in urine;Doan;Biochemical Medicine,1975

5. Rapid radiation dose assessment for radiological public health emergencies: Roles of NIAID and BARDA;Grace;Health Physics,2010

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