A CRISPR/dCasX‐mediated transcriptional programming system for inhibiting the progression of bladder cancer cells by repressing c‐MYC or activating TP53-Reference-Cited by-同舟云学术

A CRISPR/dCasX‐mediated transcriptional programming system for inhibiting the progression of bladder cancer cells by repressing c‐MYC or activating TP53

Published:2021-09 Issue:9 Volume:11 Page:
ISSN:2001-1326
Container-title:Clinical and Translational Medicine
language:en
Short-container-title:Clinical and Translational Medicine

Author:

Cao Congcong¹²³⁴⁵,Yao Lin¹²³⁴,Li Aolin¹²³⁴,Zhang Quan¹²³⁴,Zhang Zhenan¹²³⁴,Wang Xiaofei¹²³⁴,Gan Ying¹²³⁴,Liu Yuchen⁵^ORCID,Zhang Qian¹²³⁴

Affiliation:

1. Department of Urology Peking University First Hospital Beijing China

2. Institute of Urology Peking University Beijing China

3. National Urological Cancer Center Beijing China

4. Beijing Key Laboratory of Urogenital Diseases (male) Molecular Diagnosis and Treatment Center Beijing China

5. Guangdong Key Laboratory of Systems Biology and Synthetic Biology for Urogenital Tumors Shenzhen Institute of Translational Medicine, Shenzhen Second People's Hospital The First Affiliated Hospital of Shenzhen University Shenzhen China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ctm2.537

Reference7 articles.

1. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

2. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering