A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry-Reference-Cited by-同舟云学术

A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Published:2012-10-11 Issue:1 Volume:34 Page:200-209
ISSN:1059-7794
Container-title:Human Mutation
language:en
Short-container-title:Human Mutation

Author:

Thompson Bryony A.,Goldgar David E.¹,Paterson Carol²,Clendenning Mark²,Walters Rhiannon²,Arnold Sven²,Parsons Michael T.²,Michael D. Walsh²,Gallinger Steven³,Haile Robert W.⁴,Hopper John L.⁵,Jenkins Mark A.⁵,LeMarchand Loic⁶,Lindor Noralane M.⁷,Newcomb Polly A.⁸,Thibodeau Stephen N.⁹,Young Joanne P.²,Buchanan Daniel D.²,Tavtigian Sean V.¹⁰,Spurdle Amanda B.²,

Affiliation:

1. Department of Dermatology; University of Utah School of Medicine; Salt Lake City; Utah

2. Department of Genetics and Population Health; Queensland Institute of Medical Research; Herston; Brisbane; Australia

3. Cancer Care Ontario, Department of Surgery; Familial Gastrointestinal Cancer Registry; University of Toronto; Toronto; Ontario; Canada

4. Department of Preventive Medicine; University of Southern California; Los Angeles; California

5. Centre for Molecular, Environmental, Genetic and Analytic Epidemiology; University of Melbourne; Melbourne; Australia

6. Cancer Research Center of Hawaii; University of Hawaii at Manoa; Honolulu; Hawaii

7. Department of Health Science Research; Mayo Clinic Arizona; Scottsdale; Arizona

8. Prevention Program; Fred Hutchinson Cancer Research Center; Seattle; Washington

9. Laboratory Medicine and Pathology; Mayo Clinic; Rochester; Minnesota

10. Department of Oncological Sciences; Huntsman Cancer Institute; University of Utah School of Medicine; Salt Lake City; Utah

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/humu.22213/fullpdf

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