Novel transketolase inhibitor oroxylin A suppresses the non‐oxidative pentose phosphate pathway and hepatocellular carcinoma tumour growth in mice and patient‐derived organoids

Author:

Jia Dan1234,Liu Chunliang1,Zhu Zhenyu2,Cao Yan2,Wen Wen13,Hong Zhanying2,Liu Yue2,Liu Erdong13,Chen Long2,Chen Chun25,Gu Yanqiu25,Jiao Binghua4ORCID,Chai Yifeng2,Wang Hong‐yang13,Fu Jing13,Chen Xiaofei123ORCID

Affiliation:

1. International Cooperation Laboratory on Signal Transduction Eastern Hepatobiliary Surgery Hospital Second Military Medical University/Naval Medical University Shanghai China

2. School of Pharmacy Second Military Medical University/Naval Medical University Shanghai China

3. National Center for Liver Cancer Second Military Medical University/Naval Medical University Shanghai China

4. Department of Biochemistry and Molecular Biology College of Basic Medical Second Military Medical University/Naval Medical University Shanghai China

5. Department of Pharmacy Shanghai Ninth People's Hospital School of Medicine of Shanghai Jiao Tong University Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

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