A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization-Reference-Cited by-同舟云学术

A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization

Published:2019-07-03 Issue:5 Volume:106 Page:1083-1092
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Cheung Kit Wun Kathy¹²³,Groen Bianca D.⁴,Spaans Edwin⁴⁵,Borselen Marjolein D.⁶,Bruijn Adrianus C.J.M.⁷,Simons‐Oosterhuis Ytje⁷,Tibboel Dick⁴,Samsom Janneke N.⁷,Verdijk Robert M.⁸,Smeets Bart⁹,Zhang Lei¹⁰,Huang Shiew‐Mei²,Giacomini Kathleen M.¹,Wildt Saskia N.⁴⁶

Affiliation:

1. Department of Bioengineering and Therapeutic Sciences University of California, San Francisco San Francisco California USA

2. Office of Clinical Pharmacology Office of Translational Sciences Center for Drug Evaluation & Research US Food and Drug Administration Silver Spring Maryland USA

3. Oak Ridge Institute for Science and Education (ORISE Fellow) Oak Ridge Tennessee USA

4. Intensive Care and Department of Pediatric Surgery Erasmus MC‐Sophia Children's Hospital Rotterdam The Netherlands

5. CDTS Consulting BV & SDD Consulting BV Etten‐Leur The Netherlands

6. Department of Pharmacology and Toxicology Radboud University Nijmegen The Netherlands

7. Department of Pediatrics Erasmus MC‐Sophia Children's Hospital Rotterdam The Netherlands

8. Department of Pathology Erasmus MC Rotterdam The Netherlands

9. Department of Pathology Radboudumc Nijmegen The Netherlands

10. Office of Research and Standards Office of Generic Drugs Center for Drug Evaluation & Research US Food and Drug Administration Silver Spring Maryland USA

Funder

U.S. Department of Energy

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1516

Reference50 articles.

1. Renal Transporters in Drug Development

2. Precise comparison of protein localization among OCT, OAT, and MATE in human kidney

3. US Food and Drug Administration.In vitro metabolism‐ and transporter‐mediated drug‐drug interaction studies. Accessed September 24 2018.

4. International Council for Harmonisation.Guidance for Industry. E11 Clinical investigation of medicinal products in the pediatric population. (2000).

5. European Medicines Agency.Guideline on the investigation of drug interactions. Committee for Human Medicinal Products . Accessed April 3 2018.

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