Affiliation:
1. Delft University of Technology Process & Energy Department Faculty of Mechanical, Maritime and Materials Engineering 2628 CB Delft The Netherlands
2. Marmara University Chemical Engineering Department Faculty of Engineering 34854 İstanbul Turkey
Abstract
AbstractThe increasing prevalence of calcium pyrophosphate dihydrate (CPPD) deposition disease, a form of arthritis with high inflammatory potential, has triggered considerable interest in the search for additives to prevent CPPD crystal formation, particularly in the field of biomineralization. In this context, CPPD crystallization in aqueous solution with and without glycine, glutamic acid, or glycyl‐L‐glutamic acid as crystal‐growth modifier was experimentally investigated. The produced crystals were characterized structurally, morphologically, and in terms of their surface charge. In addition, the thermal degradation profiles of CPPD crystals obtained with and without the modifiers were characterized by TGA‐FTIR, and the major volatile product was H2O.
Subject
Industrial and Manufacturing Engineering,General Chemical Engineering,General Chemistry