Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR)

Author:

van der Mijn Johannes C.1,Chen Qiuying1,Laursen Kristian B.1,Khani Francesca23,Wang Xiaofei45,Dorsaint Princesca45,Sboner Andrea2567,Gross Steven S.1,Nanus David M.83,Gudas Lorraine J.13ORCID

Affiliation:

1. Department of Pharmacology Weill Cornell Medicine New York New York USA

2. Department of Pathology and Laboratory Medicine Weill Cornell Medicine New York New York USA

3. Department of Urology, New York Presbyterian Hospital Weill Cornell Medicine New York New York USA

4. Department of Physiology and Biophysics Weill Cornell Medicine New York New York USA

5. Englander Institute for Precision Medicine Weill Cornell Medicine New York New York USA

6. HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine Weill Cornell Medicine New York New York USA

7. Sandra and Edward Meyer Cancer Center Weill Cornell Medicine New York New York USA

8. Department of Medicine, Division of Hematology and Medical Oncology Weill Cornell Medicine New York New York USA

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

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