Polymorphism in cytochrome P4502A6 reduces the risk to head and neck cancer and modifies the treatment outcome

Author:

Yadav Vinay Kumar12,Katiyar Tridiv1,Ruwali Munindra3,Yadav Sanjay4,Singh Sudhir5,Hadi Rahat6,Bhatt Madan Lal Brahma5,Parmar Devendra12

Affiliation:

1. System Toxicology and Health Risk Assessment Group CSIR—Indian Institute of Toxicology Research Lucknow India

2. Academy of Scientific and Innovative Research (AcSIR) Ghaziabad India

3. Faculty of Science, Engineering And Technology Amity University Gurgaon India

4. All India Institute of Medical Sciences Raebareli India

5. Department of Radiotherapy King George's Medical University Lucknow India

6. Department of Radiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences Lucknow India

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology

Reference46 articles.

1. Genetic polymorphism of CYP2A6 gene and tobacco‐induced lung cancer risk in male smokers;Ariyoshi N.;Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology,2002

2. Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4 C

3. CYP2A6 genotype and the metabolism and disposition kinetics of nicotine

4. Genotypes Affecting the Pharmacokinetics of Anticancer Drugs

5. Nicotine and 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐butanone metabolism by cytochrome P450 2B6;Dicke K.E.;Drug Metabolism and Disposition: The Biological Fate of Chemicals,2005

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