Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice

Author:

Kwon Hyo-Jung12,Won Young-Suk13,Park Ogyi1,Chang Binxia1,Duryee Michael J.4,Thiele Geoffrey E.4,Matsumoto Akiko5,Singh Surendra6,Abdelmegeed Mohamed A.7,Song Byoung-Joon7,Kawamoto Toshihiro8,Vasiliou Vasilis6,Thiele Geoffrey M.4,Gao Bin1

Affiliation:

1. Laboratory of Liver Diseases; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health; Bethesda MD USA

2. College of Veterinary Medicine, Chungnam National University; Yuseong-gu Daejeon South Korea

3. Laboratory Animal Resource Center; Korea Research Institute of Bioscience and Biotechnology; Chungbuk South Korea

4. Experimental Immunology Laboratory; Omaha VA Medical Center and the University of Nebraska Medical Center; Omaha NE USA

5. Department of Social Medicine; Saga University School of Medicine; Saga Japan

6. Department of Pharmaceutical Sciences; University of Colorado; Aurora CO USA

7. Section of Molecular Pharmacology and Toxicology, Laboratory of Membrane Biochemistry and Biophysics; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health; Bethesda MD USA

8. Department of Environmental Health; University of Occupational and Environmental Health; Kitakyushu Japan

Funder

National Institutes of Health

Publisher

Wiley

Subject

Hepatology

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