Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine-Reference-Cited by-同舟云学术

Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine

Published:2015-06-04 Issue:1 Volume:98 Page:71-75
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Kaddurah-Daouk R¹²,Weinshilboum R³⁴,

Affiliation:

1. Department of Psychiatry and Behavioral Sciences; Duke University; Durham North Carolina USA

2. Duke Institute for Brain Sciences; Duke University; Durham North Carolina USA

3. Mayo Clinic, Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic; Rochester Minnesota USA

4. Center for Individualized Medicine; Mayo Clinic; Rochester Minnesota USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.134/fullpdf

Reference24 articles.

1. Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology;Kaddurah-Daouk;Clin. Pharmacol. Ther.,2014

2. Innovation: metabolomics: the apogee of the omics trilogy.;Patti;Nat. Rev. Mol. Cell. Biol.,2012

3. Cometabolism of microbes and host: implications for drug metabolism and drug-induced toxicity;Li;Clin Pharmacol Ther.,2013

4. Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept;Kaddurah-Daouk;Transl. Psychiatry.,2011

5. Pharmacometabolomics Research Network. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway;Zhu;PLoS One,2013

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