Affiliation:
1. Advanced Materials Research Group Faculty of Engineering University of Nottingham University Park Nottingham NG7 2RD UK
2. Nanoscale and Microscale Research Centre University of Nottingham University Park Nottingham NG7 2RD UK
3. Department of Materials Science and Engineering University of Sheffield Sheffield S1 3JD UK
Abstract
AbstractHighly porous, ferromagnetic glass‐ceramic P40‐Fe3O4 microspheres (125–212 µm) with enhanced cytocompatibility have been manufactured for the first time via a facile, rapid, single‐stage flame spheroidization process. Dispersions of Fe3O4 and Ca2Fe2O5 domains (≈10 µm) embedded within P40 (40P2O5‐16CaO‐24MgO‐20Na2O in mol%) phosphate‐based glass matrices show evidence for remanent magnetization (0.2 Am2 kg−1) and provide for controlled induction heating to a constant level of 41.9 °C, making these materials highly appropriate for localized magnetic hyperthermia applications. Complementary, cytocompatibility investigations confirm the suitability of P40‐Fe3O4 porous microspheres for biomedical applications. It is suggested that the flame‐spheroidization process opens up new opportunities for the development of innovative synergistic biomaterials, toward bone‐tissue regenerative applications.
Subject
Mechanical Engineering,Mechanics of Materials
Cited by
6 articles.
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