In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin‐8‐yl 4‐methyl‐3‐(morpholine‐4‐sulfonyl)benzoate [QMMSB]) and (quinolin‐8‐yl 4‐methyl‐3‐((propan‐2‐yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testing

Author:

Richter Matthias J.1,Wagmann Lea1ORCID,Kavanagh Pierce V.2,Brandt Simon D.3ORCID,Meyer Markus R.1ORCID

Affiliation:

1. Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS) Saarland University Homburg Germany

2. Department of Pharmacology and Therapeutics, School of Medicine Trinity Centre for Health Sciences, St. James Hospital Dublin 8 Ireland

3. School of Pharmacy and Biomolecular Sciences Liverpool John Moores University Liverpool UK

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference26 articles.

1. UNODC.World Drug Report 2021 (United Nations publication Sales No. E.21.XI.8).https://www.unodc.org/res/wdr2021/field/WDR21_Booklet_2.pdf. Accessed August 11 2022.

2. A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment

3. EMCDDA.European Drug Report 2022 ‐ Trends and Developments.2022.https://www.emcdda.europa.eu/system/files/publications/14644/TDAT22001ENN.pdf. Accessed August 11 2022.

4. EMCDDA.Perspectives on drugs Synthetic cannabinoids in Europe.2017.https://www.emcdda.europa.eu/system/files/publications/2753/POD_Synthetic%20cannabinoids_0.pdf. Accessed August 11 2022.

5. Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: Identification of a lead and initial SAR studies

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