In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin‐8‐yl 4‐methyl‐3‐(morpholine‐4‐sulfonyl)benzoate [QMMSB]) and (quinolin‐8‐yl 4‐methyl‐3‐((propan‐2‐yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testing-Reference-Cited by-同舟云学术

In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin‐8‐yl 4‐methyl‐3‐(morpholine‐4‐sulfonyl)benzoate [QMMSB]) and (quinolin‐8‐yl 4‐methyl‐3‐((propan‐2‐yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testing

Published:2022-10-26 Issue:2 Volume:15 Page:181-191
ISSN:1942-7603
Container-title:Drug Testing and Analysis
language:en
Short-container-title:Drug Testing and Analysis

Author:

Richter Matthias J.¹,Wagmann Lea¹^ORCID,Kavanagh Pierce V.²,Brandt Simon D.³^ORCID,Meyer Markus R.¹^ORCID

Affiliation:

1. Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS) Saarland University Homburg Germany

2. Department of Pharmacology and Therapeutics, School of Medicine Trinity Centre for Health Sciences, St. James Hospital Dublin 8 Ireland

3. School of Pharmacy and Biomolecular Sciences Liverpool John Moores University Liverpool UK

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/dta.3385

Reference26 articles.

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2. A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment

3. EMCDDA.European Drug Report 2022 ‐ Trends and Developments.2022.https://www.emcdda.europa.eu/system/files/publications/14644/TDAT22001ENN.pdf. Accessed August 11 2022.

4. EMCDDA.Perspectives on drugs Synthetic cannabinoids in Europe.2017.https://www.emcdda.europa.eu/system/files/publications/2753/POD_Synthetic%20cannabinoids_0.pdf. Accessed August 11 2022.

5. Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: Identification of a lead and initial SAR studies

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