Characterisation of a P140K mutantO6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow-Reference-Cited by-同舟云学术

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Characterisation of a P140K mutantO6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow

Published:2006 Issue:9 Volume:8 Page:1071-1085
ISSN:1099-498X
Container-title:The Journal of Gene Medicine
language:en
Short-container-title:J. Gene Med.

Author:

Kramer Belinda A.,Lemckert Frances A.,Alexander Ian E.,Gunning Peter W.,McCowage Geoffrey B.

Publisher

Wiley

Subject

Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference52 articles.

1. Clinical Relevance of MGMT in the Treatment of Cancer

2. Repair of O6-alkylguanine by alkyltransferases

3. Genetic Chemoprotection with Mutant O6-Alkylguanine-DNA-Alkyltransferases

4. Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea

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1. Potential Applications for Targeted Gene Therapy to Protect Against Anthracycline Cardiotoxicity;JACC: CardioOncology;2021-12

2. Clinical Trial ofMGMT(P140K)Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors;Human Gene Therapy;2018-08

3. Methyl-Guanine-Methyl-Transferase Transgenic Bone Marrow Transplantation Allows N,N-bis(2-chloroethyl)-Nitrosourea Driven Donor Mixed-Chimerism Without Graft-Versus-Host Disease, and With Donor-Specific Allograft Tolerance;Transplantation;2015-12

4. Repair mechanisms help glioblastoma resist treatment;Journal of Clinical Neuroscience;2015-01

5. Engraftment and Lineage Potential of Adult Hematopoietic Stem and Progenitor Cells Is Compromised Following Short-Term Culture in the Presence of an Aryl Hydrocarbon Receptor Antagonist;Human Gene Therapy Methods;2014-08

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