Aquaporin-4 knockout mice exhibit increased hypnotic susceptibility to ketamine

Author:

Lv Yunluo1,Dai Wangshu2ORCID,Ge Ai3,Fan Yi4,Hu Gang4,Zeng Yinming5

Affiliation:

1. Department of Anesthesiology; Nanjing First Hospital; Nanjing Medical University; Nanjing China

2. The Comprehensive Cancer Centre of Drum Tower Hospital; Medical School of Nanjing University; Clinical Cancer Institute of Nanjing University; Nanjing China

3. Department of Respiratory Medicine; Tongji Hospital; Tongji University School of Medicine; Shanghai China

4. Jiangsu Key Laboratory of Neurodegeneration; Department of Pharmacology; Nanjing Medical University; Nanjing China

5. Jiangsu Province Institute of Anesthesiology; Xuzhou Medical University; Xuzhou China

Funder

National Natural Science Foundation of China

Jiangsu Province Scientific Research Innovation Project

Publisher

Wiley

Subject

Behavioral Neuroscience

Reference42 articles.

1. Anchoring of aquaporin-4 in brain: Molecular mechanisms and implications for the physiology and pathophysiology of water transport;Amiry-Moghaddam;Neuroscience,2004

2. The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid;Belelli;Proceedings of the National Academy of Sciences of the United States of America,1997

3. Neuron-astrocyte interactions: Partnership for normal function and disease in the central nervous system;Benarroch;Mayo Clinic Proceedings,2005

4. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels;Binder;Glia,2006

5. Behavioral tolerance and sensitization to CGS 19755, a competitive N-methyl-D-aspartate receptor antagonist;Boast;Journal of Pharmacology and Experimental Therapeutics,1988

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