Targeted Notch1 inhibition with a Notch1 antibody, OMP‐A2G1, decreases tumor growth in two murine models of prostate cancer in association with differing patterns of DNA damage response gene expression
Author:
Affiliation:
1. Department of Urology University of Michigan Ann Arbor Michigan
2. Biointerfaces Institute University of Michigan Ann Arbor Michigan
Funder
National Institutes of Health
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.28954
Reference31 articles.
1. Notch signaling in prostate cancer: refining a therapeutic opportunity;Su Q;Histol Histopathol,2016
2. NOTCH and PTEN in prostate cancer
3. Androgen Receptor Promotes the Oncogenic Function of Overexpressed Jagged1 in Prostate Cancer by Enhancing Cyclin B1 Expression via Akt Phosphorylation
4. Hey1, a Mediator of Notch Signaling, Is an Androgen Receptor Corepressor
5. Notch Pathway Inhibition Using PF-03084014, a γ-Secretase Inhibitor (GSI), Enhances the Antitumor Effect of Docetaxel in Prostate Cancer
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