Bevacizumab biosimilar LY01008 compared with bevacizumab (Avastin) as first‐line treatment for Chinese patients with unresectable, metastatic, or recurrent non‐squamous non–small‐cell lung cancer: A multicenter, randomized, double‐blinded, phase III trial

Author:

Shi Yuankai1ORCID,Lei Kaijian2,Jia Yuming2,Ni Bingqiang3,He Zhiyong4,Bi Minghong5,Wang Xicheng6,Shi Jianhua7,Zhou Ming8,Sun Qian9,Wang Guolei9,Chen Dongji10,Shu Yongqian11ORCID,Liu Lianke11,Guo Zhongliang12,Liu Yong13,Yang Junquan14,Wang Ke15,Xiao Ke16,Wu Lin17,Yi Tienan18,Sun Debin19,Kang Mafei20,Ma Tianjiang21,Mao Yimin22,Shi Jinsheng23,Tang Tiegang24,Wang Yan1,Xing Puyuan1,Lv Dongqing25,Liao Wangjun26,Luo Zhiguo27,Wang Bin28,Wu Xiaohong29,Zhu Xiaoli30,Han Shuhua30,Guo Qisen31,Liu Rongyu32,Lu Zhiwei33,Zhang Jianyong34,Fang Jian35,Hu Changlu36,Ji Yinghua37,Liu Guolong38,Lu Hong39,Wu Dedong40,Zhang Junhong41,Zhu Shuyang42,Liu Zheng43,Qiu Wensheng44,Ye Feng45,Yu Yan46,Zhao Yanqiu47,Zheng Qinhong48,Chen Jun49,Pan Zhanyu50,Zhang Yiping51,Lian Wenjuan52,Jiang Bo53,Qiu Bo54,Zhang Guojun55,Zhang Hua56,Chen Yanju57,Chen Yuan58,Duan Hongbing59,Li Manxiang60,Liu Shengming61,Ma Lijun62,Pan Hongming63,Yuan Xia64,Yuan Xueli65,Zheng Yulong66,Gao Emei67,Zhao Li67,Wang Shumin67,Wu Can67

Affiliation:

1. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs Beijing 100021 P. R. China

2. Department of Oncology Yibin Second People's Hospital Yibin Sichuan 644000 P. R. China

3. Department of Oncology Liuzhou People's Hospital Liuzhou Guangxi 545006 P. R. China

4. Department of Thoracic Oncology Fujian Provincial Cancer Hospital Fuzhou Fujian 350014 P. R. China

5. Oncology Department the First Affiliated Hospital of Bengbu Medical College Bengbu Anhui 233030 P. R. China

6. Department of Oncology the First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou Guangdong 510030 P. R. China

7. Department of Internal medicine Linyi Cancer Hospital Linyi Shandong 276002 P. R. China

8. Department of Thoracic Surgery the Affiliated Cancer Hospital of Guangzhou Medical University Guangzhou Guangdong 510095 P. R. China

9. Department of Internal Medicine‐Oncology/Department of thoracic oncology Henan Chest Hospital Zhengzhou Henan 450003 P. R. China

10. The Second Department of Radiotherapy Wuwei Cancer Hospital of Gansu Province Wuwei Gansu 730000 P. R. China

11. Department of Oncology the People's Hospital of Jiangsu Province Nanjing Jiangsu 210000 P. R. China

12. Respiratory Medicine Department Shanghai East Hospital Shanghai 200120 P. R. China

13. The Second Department of Internal Medicine‐Oncology Xuzhou Central Hospital Xuzhou Jiangsu 221009 P. R. China

14. Oncology Department Tangshan People's Hospital Tangshan Hebei 063001 P. R. China

15. Respiratory Medicine Department West China Hospital of Sichuan University Chengdu Sichuan 610041 P. R. China

16. Thoracic Surgery the Second Affiliated Hospital of Shantou University Medical College Shantou Guangdong 515051 P. R. China

17. Internal Medicine‐Oncology Hunan Cancer Hospital Changsha Hunan 410013 P. R. China

18. Department of Oncology Xiangyang Central Hospital Xiangyang Hubei 441021 P. R. China

19. Respiratory Department Lishui Central Hospital Lishui Zhejiang 323000 P. R. China

20. Oncology Department The Affiliated Hospital of Guilin Medical College Guilin Guangxi 541001 P. R. China

21. Internal Medicine‐Oncology Luohe Central Hospital Luohe Henan 462000 P. R. China

22. Respiratory Department the First Affiliated Hospital of Henan University of Science and Technology Luoyang Henan 471003 P. R. China

23. Oncology Department Cangzhou People's Hospital Cangzhou Hebei 061000 P. R. China

24. Oncology Department Xiangtan Central Hospital Xiangtan Hunan 411100 P. R. China

25. Respiratory Department Taizhou Hospital of Zhejiang Province Taizhou Zhejiang 317000 P. R. China

26. Department of Oncology Nanfang Hospital of Southern Medical University Guangzhou Guangdong 510515 P. R. China

27. Department of Oncology Taihe Hospital of Shiyan City Shiyan Hubei 442000 P. R. China

28. Respiratory Department Huzhou Central Hospital Huzhou Zhejiang 313003 P. R. China

29. Internal Medicine‐Oncology the Fourth People's Hospital of Wuxi City Wuxi Jiangsu 214062 P. R. China

30. Department of Oncology Zhongda Hospital of Southeast University Nanjing Jiangsu 210009 P. R. China

31. The Second Department of Internal Medicine Shandong Cancer Hospital Jinan Shandong 250117 P. R. China

32. Respiratory Department the First Affiliated Hospital of Anhui Medical University Hefei Anhui 230022 P. R. China

33. Respiratory Department The First Affiliated Hospital of Wannan Medical College Wuhu Anhui 241001 P. R. China

34. The Second Department of Respiratory Medicine the Affiliated Hospital of Zunyi Medical College Zunyi Guizhou 563099 P. R. China

35. The Second Department of thoracic oncology Beijing Cancer Hospital Beijing 100142 P. R. China

36. Department of Oncology Anhui Cancer Hospital Hefei Anhui 233004 P. R. China

37. Oncology Department the First Affiliated Hospital of Xinxiang Medical College Xinxiang Henan 453100 P. R. China

38. Department of Oncology the First People's Hospital of Guangzhou Guangzhou Guangdong 510180 P. R. China

39. Oncology Department Huaihe Hospital of Henan University Kaifeng Henan 475000 P. R. China

40. Department of Oncology and Hematology The First People's Hospital of Zhengzhou Zhengzhou Henan 450004 P. R. China

41. Oncology Department Zhongnan Hospital of Wuhan University Wuhan Hubei 430071 P. R. China

42. Respiratory Department The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221006 P. R. China

43. The Third Department of Oncology Handan Central Hospital Handan Hebei 056001 P. R. China

44. Oncology Department The Affiliated Hospital of Qingdao University Qingdao Shandong 266011 P. R. China

45. Oncology Department the First Affiliated Hospital of Xiamen University Xiamen Fujian 361003 P. R. China

46. The Sixth Department of Internal Medicine the Affiliated Cancer Hospital of Harbin Medical University Harbin Heilongjiang 150081 P. R. China

47. Respiratory Department Henan Cancer Hospital Zhengzhou Henan 450008 P. R. China

48. Internal Medicine‐Oncology Quzhou People's Hospital Quzhou Zhejiang 324000 P. R. China

49. Lung tumor surgery Department General Hospital of Tianjin Medical University Tianjin 300052 P. R. China

50. Integrated Traditional Chinese and Western Medicine Department Tianjin Cancer Hospital Tianjin 300060 P. R. China

51. Department of Thoracic Cancer Zhejiang Cancer Hospital Hangzhou Zhejiang 310022 P. R. China

52. Department of Oncology Xi'an Chest Hospital Xi'an Shanxi 710061 P. R. China

53. Special Medical Treatment Yunnan Cancer Hospital Kunming Yunnan 650106 P. R. China

54. Department of Oncology Zhuzhou Central Hospital Zhuzhou Hunan 412007 P. R. China

55. Respiratory Department The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 P. R. China

56. Second Department of Cancer Center The First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 P. R. China

57. Internal Medicine‐Oncology Hainan Provincial People's Hospital Haikou Hainan 570311 P. R. China

58. Oncology Department Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 P. R. China

59. Thoracic Surgery Zhongshan Hospital Affiliated to Xiamen University Xiamen Fujian 361004 P. R. China

60. Respiratory Department The First Affiliated Hospital of Xi'an Jiaotong University Xi'an Shanxi 710061 P. R. China

61. Respiratory Department The First Affiliated Hospital of Jinan University Guangzhou Guangdong 510632 P. R. China

62. Oncology Department Shanghai Tongren Hospital Shanghai 200336 P. R. China

63. Internal Medicine‐Oncology Shaoyifu Hospital Affiliated to Medical College of Zhejiang University Hangzhou Zhejiang 310016 P. R. China

64. Internal Medicine‐Oncology Huizhou Central People's Hospital Huizhou Guangdong 516008 P. R. China

65. Oncology Department the Fourth Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 P. R. China

66. Respiratory Department Huai'an Second People's Hospital Huai'an Jiangsu 223002 P. R. China

67. Clinical Research Center of Luye Pharma Group Ltd Luye Life Sciences Group Beijing 100025 P. R. China

Publisher

Wiley

Subject

Cancer Research,Oncology

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