Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1‐mediated MAPK signaling

Author:

He Luwei12ORCID,Li Huaguang12,Pan Chenyu12,Hua Yutong12,Peng Jiayin3,Zhou Zhaocai4,Zhao Yun35,Lin Moubin126

Affiliation:

1. Center for Clinical Research and Translational Medicine Yangpu Hospital Tongji University School of Medicine Shanghai 200090 P. R. China

2. Institute of Gastrointestinal Surgery and Translational Medicine Tongji University School of Medicine Shanghai 200090 P. R. China

3. The State Key Laboratory of Cell Biology CAS Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology University of Chinese Academy of Sciences Chinese Academy of Sciences Shanghai 200031 P. R. China

4. State Key Laboratory of Genetic Engineering School of Life Sciences Zhongshan Hospital Fudan University Shanghai 200438 P. R. China

5. School of Life Science and Technology ShanghaiTech University Shanghai 201210 P. R. China

6. Department of General Surgery Yangpu Hospital Tongji University School of Medicine Shanghai 200090 P. R. China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

Shanghai Municipal Health Bureau

Publisher

Wiley

Subject

Cancer Research,Oncology

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