Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues forin vivomass spectrometric quantification

Author:

Subramanian Thangaiah1,Subramanian Karunai Leela2,Sunkara Manjula2,Onono Fredrick O.1,Morris Andrew J.,Spielmann H. Peter

Affiliation:

1. Department of Molecular and Cellular Biochemistry; University of Kentucky; Lexington; KY; 40536; USA

2. Division of Cardiovascular Medicine UK COM; University of Kentucky; Lexington; KY; 40536; USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference44 articles.

1. Regulation of the mevalonate pathway;Goldstein;Nature,1990

2. Origins and early evolution of the mevalonate pathway of isoprenoid biosynthesis in the three domains of life;Lombard;Mol. Biol. Evol.,2011

3. Statins and protein prenylation in cancer cell biology and therapy;Garcia-Ruiz;Anti-Cancer Agents Med Chem,2012

4. National Cholesterol Education-Program, 2nd Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults;Rubinstein;Circulation,1995

5. National Cholesterol Education-Program, 2nd Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults - Reply;Grundy;Circulation,1995

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