Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes-Reference-Cited by-同舟云学术

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Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes

Published:2010-02-17 Issue:4 Volume:54 Page:532-542
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

Vauzour David,Buonfiglio Maria,Corona Giulia,Chirafisi Joselita,Vafeiadou Katerina,Angeloni Cristina,Hrelia Silvana,Hrelia Patrizia,Spencer Jeremy P. E.

Funder

Biotechnology and Biological Sciences Research Council

Medical Research Council

MIUR-COFIN 2007 (project ♯ AYMLF) Italy

Biomedical Research Centre University of Dundee

Publisher

Wiley

Subject

Food Science,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mnfr.200900197/fullpdf

Reference58 articles.

1. Dopamine receptors and brain function;Jaber;Neuropharmacology,1996

2. The pathogenesis of cell death in Parkinson's disease - 2007;Olanow;Mov. Disord.,2007

3. 5-S-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons;Spencer;J. Neurochem.,2002

4. Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols;Vauzour;Arch. Biochem. Biophys.,2008

5. Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols;Vauzour;Biochem. Biophys. Res. Commun.,2007

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