Bisphosphonate Induces Osteonecrosis of the Jaw in Diabetic Mice via NLRP3/Caspase-1-Dependent IL-1β Mechanism

Author:

Zhang Qunzhou1,Yu Weihua1,Lee Sumin1,Xu Qilin1,Naji Ali2,Le Anh D13

Affiliation:

1. Department of Oral and Maxillofacial Surgery and Pharmacology; University of Pennsylvania School of Dental Medicine; Philadelphia PA USA

2. Division of Transplantation, Department of Surgery; Perelman School of Medicine at the University of Pennsylvania; Philadelphia PA USA

3. Department of Oral and Maxillofacial Surgery; Penn Medicine Hospital of the University of Pennsylvania, Philadelphia; PA USA

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Reference56 articles.

1. Epidemiology and pathogenesis of osteonecrosis of the jaw;Reid;Nat Rev Rheumatol.,2012

2. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws-2009 update;Ruggiero;J Oral Maxillofac Surg.,2009

3. Osteonecrosis of the jaw in patients with multiple myeloma treated with zoledronic acid;Cetiner;J Bone Miner Metab.,2009

4. A retrospective study evaluating frequency and risk factors of osteonecrosis of the jaw in 576 cancer patients receiving intravenous bisphosphonates;Thumbigere-Math;Am J Clin Oncol.,2012

5. Human skin wounds: a major and snowballing threat to public health and the economy;Sen;Wound Repair Regen.,2009

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