Treatment of relapsed/refractory severe aplastic anemia in children: Evidence‐based recommendations

Author:

Shimano Kristin A.1ORCID,Sasa Ghadir2,Broglie Larisa3ORCID,Gloude Nicholas J.4,Myers Kasiani5ORCID,Nakano Taizo A.6ORCID,Sharathkumar Anjali7ORCID,Rothman Jennifer A.8ORCID,Pereda Maria A.6,Overholt Kathleen9,Narla Anupama10,McGuinn Catherine11,Lau Bonnie W.12ORCID,Geddis Amy E.13,Dror Yigal14ORCID,de Jong Jill L. O.15,Castillo Paul16ORCID,Allen Steven W.17,Boklan Jessica18ORCID

Affiliation:

1. Department of Pediatrics, Division of Allergy Immunology, and Bone Marrow Transplant University of California San Francisco Benioff Children's Hospital San Francisco California USA

2. Sarah Cannon Transplant and Cellular Therapy Network San Antonio Texas USA

3. Department of Pediatric Hematology/Oncology/Blood and Marrow Transplantation Medical College of Wisconsin Milwaukee Wisconsin USA

4. Department of Pediatrics University of California San Diego Rady Children's Hospital San Diego California USA

5. Department of Pediatrics Division of Bone Marrow Transplantation and Immune Deficiency University of Cincinnati College of Medicine Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA

6. Department of Pediatrics, Center for Cancer and Blood Disorders Children's Hospital Colorado Aurora Colorado USA

7. Stead Family Department of Pediatrics University of Iowa Carver College of Medicine Iowa City Iowa USA

8. Division of Pediatric Hematology/Oncology Duke University Medical Center Durham North Carolina USA

9. Department of Pediatrics, Pediatric Hematology/Oncology Riley Hospital for Children at Indiana University Indianapolis Indiana USA

10. Department of Pediatrics Stanford University School of Medicine Stanford California USA

11. Department of Pediatrics, Division of Pediatric Hematology Oncology Weill Cornell Medicine New York New York USA

12. Department of Pediatrics, Pediatric Hematology‐Oncology Dartmouth‐Hitchcock Lebanon Pennsylvania USA

13. Department of Paediatrics Division of Hematology/Oncology Cancer and Blood Disorders Center Seattle Children's Hospital Seattle Washington USA

14. Department of Pediatrics, Marrow Failure and Myelodysplasia Program The Hospital for Sick Children Toronto Canada

15. Department of Pediatrics Section of Hematology/Oncology/Stem Cell Transplantation University of Chicago Chicago Illinois USA

16. Department of Pediatrics, Division of Pediatric Hematology Oncology UF Health Shands Children's Hospital Gainesville Florida USA

17. Department of Pediatrics, Pediatric Hematology/Oncology University of Pittsburgh School of Medicine UPMC Children's Hospital of Pittsburgh Pittsburgh Pennsylvania USA

18. Department of Pediatrics, Center for Cancer and Blood Disorders Phoenix Children's Hospital Phoenix Arizona USA

Abstract

AbstractSevere aplastic anemia (SAA) is a rare potentially fatal hematologic disorder. Although overall outcomes with treatment are excellent, there are variations in management approach, including differences in treatment between adult and pediatric patients. Certain aspects of treatment are under active investigation in clinical trials. Because of the rarity of the disease, some pediatric hematologists may have relatively limited experience with the complex management of SAA. The following recommendations reflect an up‐to‐date evidence‐based approach to the treatment of children with relapsed or refractory SAA.

Publisher

Wiley

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3