Quantitative intracellular flux modeling and applications in biotherapeutic development and production using CHO cell cultures-Reference-Cited by-同舟云学术

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Quantitative intracellular flux modeling and applications in biotherapeutic development and production using CHO cell cultures

Published:2017-09-11 Issue:12 Volume:114 Page:2717-2728
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Huang Zhuangrong¹,Lee Dong-Yup²³,Yoon Seongkyu¹^ORCID

Affiliation:

1. Department of Chemical Engineering, University of Massachusetts Lowell; One University Avenue; Lowell Massachusetts

2. Department of Chemical and Biomolecular Engineering; National University of Singapore; Singapore Singapore

3. Bioprocessing Technology Institute; Agency for Science, Technology and Research (A*STAR); Singapore Singapore

Funder

University of Massachusetts Lowell, Masschusetts Biomanufacturing Center

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference109 articles.

1. Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry;Ahn;Metabolic Engineering,2011

2. Towards dynamic metabolic flux analysis in CHO cell cultures;Ahn;Biotechnology Journal,2012

3. Parallel labeling experiments with [1,2-(13)C]glucose and [U-(13)C]glutamine provide new insights into CHO cell metabolism;Ahn;Metabolic Engineering,2013

4. Evidence for transketolase-like TKTL1 flux in CHO cells based on parallel labeling experiments and (13)C-metabolic flux analysis;Ahn;Metabolic Engineering,2016

5. Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control;Altamirano;Biotechnology and Bioengineering,2001

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