Development of an innovative minimally invasive primate spinal cord injury model: A case report-Reference-Cited by-同舟云学术

Development of an innovative minimally invasive primate spinal cord injury model: A case report

Published:2023-07-10 Issue:3 Volume:9 Page:349-356
ISSN:2313-1934
Container-title:Ibrain
language:en
Short-container-title:Ibrain

Author:

Niu Yong‐Min¹^ORCID,Liu Jin‐Xiang¹^ORCID,Qin Hao‐Yue²^ORCID,Liu Yi‐Fan³,Huang Ni‐Jiao⁴,Jiang Ji‐Li¹,Chen Yan‐Qiu⁵,Chen Si‐Jing⁶,Bai Tao⁷,Yang Chang‐Wei⁸,Cao Yu⁸,Liu Sheng⁹,Yuan Hao⁴^ORCID

Affiliation:

1. Institute of Neuroscience Kunming Medical University Kunming Yunnan China

2. Department of Anesthesiology Southwest Medical University Luzhou Sichuan China

3. Yunnan Cancer Hospital The Third Affiliated Hospital of Kunming Medical University Yunnan China

4. Department of Orthopaedic Surgery Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China

5. School of Preclinical Medical Zunyi Medical University Zunyi Guizhou China

6. Nursing School Zunyi Medical University Zunyi Guizhou China

7. School of Preclinical Medical Kunming Medical University Kunming Yunnan China

8. Department of Nuclear Medicine Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China

9. Pharmacology Institute Heidelberg University Heidelberg Germany

Abstract

AbstractSpinal cord injury (SCI) animal models have been widely created and utilized for repair therapy research, but more suitable experimental animals and accurate modeling methodologies are required to achieve the desired results. In this experiment, we constructed an innovative dorsal 1/4 spinal cord transection macaque model that had fewer severe problems, facilitating postoperative care and recovery. In essence, given that monkeys and humans share similar genetics and physiology, the efficacy of this strategy in a nonhuman primate SCI model basically serves as a good basis for its prospective therapeutic use in human SCI.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ibra.12117

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