Probing the solution structure of tumor necrosis factor-α homotrimer and heterotrimer after complex perturbation using electrospray ionization mass spectrometry
Author:
Affiliation:
1. Centocor Research and Development; a division of J&J PRD, 145 King of Prussia Rd; Radnor; PA; 19087; USA
Publisher
Wiley
Subject
Molecular Biology,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jmr.1170/fullpdf
Reference24 articles.
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2. Heterotrimers formed by tumor necrosis factors of different species or muteins;Ameloot;J. Biol. Chem.,2001
3. Mass spectrometry of macromolecular assemblies: preservation and dissociation;Benesch;Curr. Opin. Struc. Biol.,2006
4. High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity;Cha;J. Biol. Chem.,1998
5. Oligomeric tumer necrosis factor α slowly converts into inactive forms at bioactive levels;Corti;Biochem. J.,1992
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